A case of anhidrosis and widespread vitiligo-like depigmentation with metastatic melanoma immunotherapy

We present a case of a 37-year old male with widespread depigmentation and marked reduction in sweating on a background of metastatic melanoma on a clinical trial of Nivolumab vs. Ipilimumab vs. combination therapy. A concurrent adverse effect was thyroiditis treated with thyroxine. A thermal starch-iodine sweat test (oral temperature increased to 37.6 degrees for … Continue reading A case of anhidrosis and widespread vitiligo-like depigmentation with metastatic melanoma immunotherapy