Abstract Number: 102

A review on the current management of incidental perineural invasion in nonmelanoma skin cancer: The need for a registry

L. Buchanan , B. De ’ Ambrosis , B. Panizza , K. DeAmbrosis , H.P. Soyer

Meeting: 2013 Dermcoll

Session Information

Date: -

Session Title: Poster Presentations

Session Time: -

This position statement by the Perineural Invasion (PNI) Registry aims to clarify clinical and histopathological ambiguities surrounding perineural invasion in nonmelanoma skin cancer. PNI is reportedly present in 0.18% to 10% of basal cell carcinomas and 2.5% to 14% of squamous cell carcinomas and is associated with greater rates of morbidity and mortality. The distinction between clinical PNI and incidental PNI is somewhat unclear, especially in regard to management and prognosis. One important objective of the PNI registry, which was established in 2010 as a collaborative effort by the Queensland Perineural Invasion Groupand is available at https://intranet.som.uq.edu.au/PNIRegistry/ , isto develop a standardised method of classifying perineu- ralinvasion. Hence, in this position statement we propose a defi nition for PNI and for its sub-classifi cation.
This position also provides a critical analysis of the current literature regarding the treatment of incidental PNI. At present, there are no universal clinical guidelines that specify acceptable treatment of skin cancers exhibiting incidental PNI. Subsequently, patients often receive surgery with varying wider margins, and/or radiotherapy despite the limited evidence substantiating such management options. The PNI registry has been developed to assist in attaining further data pertaining to incidental PNI in NMSC. Thus, the ultimate aim of the PNI registry is to identify and defi ne best practice in managing incidental PNI.