A. Boyapati , M.Tam , R.L. Nixon
Methylchloroisothiazolinone/methylisothiazolinone (MI/ MCI) is a common preservative used in cosmetic products and is a well-established cause of allergic contact dermatitis (ACD). In 2005, MI alone was approved for use in cosmetic products, with a maximum permitted concentration of 25 times that allowed in the MI/MCI combination . In August 2010, the ﬁ rst cases of MI causing ACD to cosmetic products were published, with reactions occurring to MI in shampoos, conditioners, liquid soaps, moist toilet tissues and makeup remover. We report a series of cases from the Skin and Cancer Foundation in Victoria, of ACD occurring on the hands of parents who have used baby wipes (Huggies™ and Mamia™ brands), where MI was shown to be the causative allergen. We also report cases of ACD to MI in other cosmetic products, including facial moisturising creams and a shampoo. This case series provides further evidence that MI is an emerging allergen in cosmetic products, and is the ﬁ rst reported series anywhere demonstrating that ACD to MI in baby wipes is an important cause of hand dermatitis in parents.
A non-interventional-prospective-12-month study to characterise REAL-life effectiveness and treatmentpatterns of secukinumab, and current standard-of-care of chronic plaque psoriasis in Asia-Pacific & MiddleEast