Abstract Number: 12

Combining laser and light PDT

G. Goodman

Meeting: 2013 Dermcoll

Session Information

Date: -

Session Title: Lasers Symposium

Session Time: -

In the visible light spectrum (500–700 nm), lasers may treat a variety of pigmented lesions or vascular lesions. Lentigines, freckles, seborrhoeic keratoses and pigmented solar keratoses can be targeted with the appropriate laser parameters. Similarly vascular lasers can treat such entities such as spider nevi, telangiectasia, and port wine stains as well as fl ushing disorders and widespread vascular abnormalities. Intense pulsed lights are different to lasers in their application as they use a broad band of wavelengths which are added together over a truncated part of the total spec- trum to achieve an effect similar to lasers. Adding porphyrins (usually in the form of amino levulinic acid or ALA) to the skin allows these visible lights and lasers to fi nd other targets. Photodynamic therapy (PDT) can be used to treat diverse conditions such as solar damage and early skin cancers as well as acne and is utilised with aminolevulinic acid or methyl aminolevulinic acid and the appropriate wavelength of light that may be blue, green, red or yellow. Once the target has been stimulated by the absorption of ALA or similar products then the light will stimulate that cell to apoptosis by the addition of the appro- priate wavelength of light. Acne is reasonably well treated with this treatment as both the P acnes and sebaceous glands are rich in natural porphyrins and are able to metabolise exogenous porphyrins allowing further targeting by lights or lasers