B. Carew, B. Byrom, J. Muir
Although Seborrheic keratosis (SK) is generally regarded as a benign tumour there are numerous reports of SK and malignancy. The exact incidence of melanoma associated with SK is unknown although it has been reported as between 0.3 and 0.66% Argenziano et al. have previously cautioned about the potential to miss melanoma when speciﬁ c criteria for seborrheic keratosis, such as comedo like openings, are present . Cassangrande et al. have presented an approach for dermoscopy of SK-like lesions in an attempt to reduce this risk . This involves blocking out the lesion and actively scanning all quadrants for other features. This approach may reduce factors such as search satisfaction and conﬁ rmational bias. We present two cases of melanoma associated with SK with discussion of dermatoscopic features. The presented cases further illustrate the importance of clinical change as a trigger for further examination and also the danger in relying solely on dermoscopy for exclusion of melanoma.