D. Mazzoni1 , R. Mortimore2, L. Wheller1, S. Bodapati1, J. Davies
Crohn’s disease is a chronic inﬂammatory disease charac- teristically known to affect the gastrointestinal tract any- where from mouth to anus. While extraintestinal manifestations such as uveitis and arthritis are relatively common, penile Crohn’s disease is a far less common manifestation. Moreover, the onset of cutaneous and mucosal lesions typically proceeds involvement of the bowel. We present the case of a 14-year old-male who pre- sented with a 2-month history of penile swelling. A genital biopsy of the lesion demonstrated non-caseating granulo- mas consistent with penile Crohn’s disease. Our patient responded well to inﬂiximab therapy. Unusual presenta- tions can make the diagnosis challenging, and therefore highlights the importance of histopathological examination if clinically suspected to avoid delays in diagnosis and commencement of treatment. The most efﬁcacious treat- ments for penile Crohn’s disease remains largely unknown due to limited data in this area.