N. Chinniah , C.J.A. Henderson , G.D. Cains
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a distinctive skin lymphoma that is characterised by inﬁ ltration of the subcutaneous tissue by neoplastic T cells mimicking panniculitis. It is an exceedingly rare condition thought to represent less than 1% of all non-Hodgkin’s lymphoma . SPTLC can often be difﬁ cult to differentiate from a benign panniculitis due to similarities in clinical and histological features between the two entities. It can also be a challenge to distinguish SPTCL from other T-cell lymphomas that can present in the subcutis, especially as the deﬁ nition has continued to evolve over recent years. We present experience of this condition from a large tertiary hospital in Sydney. Cases were identiﬁ ed through a comprehensive search of the hospital pathology and Cerner databases using keywords. From our case series we will present data on the patient’s initial presentation, area of initial involvement, the diagnostic tests including the haematological markers, histological ﬁ ndings as well as describe the treatment options and patient outcome. Previously thought to be an aggressive entity our experience has been that of an indolent process. SPTCL is a rare condition and our case series will help illustrate the clinical presentation, diagnostic pathway and management process.